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β-cyclodextrin sulfobutyl ether sodium salt (captisol)  (Cydex Inc)

 
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    Structured Review

    Cydex Inc β-cyclodextrin sulfobutyl ether sodium salt (captisol)
    Three-dimensional inclusion pockets of (A) β-CD, (B) HP β-CD and (C) <t>Captisol</t> demonstrating (i) top view, (ii) bottom view (iii) side view (iv) top view with outlined interactions showing the bond lengths.
    β Cyclodextrin Sulfobutyl Ether Sodium Salt (Captisol), supplied by Cydex Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/%CE%B2-cyclodextrin+sulfobutyl+ether+sodium+salt+%28captisol%29/pmc12136891-68-15-25?v=Cydex+Inc
    Average 90 stars, based on 1 article reviews
    β-cyclodextrin sulfobutyl ether sodium salt (captisol) - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Formulation, in silico, in vitro characterization, cytotoxicity and cellular uptake of cyclodextrin complexes and ion pairing/salt formation with functional excipients (azelaic acid, tartaric acid, and arginine) with raloxifene"

    Article Title: Formulation, in silico, in vitro characterization, cytotoxicity and cellular uptake of cyclodextrin complexes and ion pairing/salt formation with functional excipients (azelaic acid, tartaric acid, and arginine) with raloxifene

    Journal: International Journal of Pharmaceutics: X

    doi: 10.1016/j.ijpx.2025.100336

    Three-dimensional inclusion pockets of (A) β-CD, (B) HP β-CD and (C) Captisol demonstrating (i) top view, (ii) bottom view (iii) side view (iv) top view with outlined interactions showing the bond lengths.
    Figure Legend Snippet: Three-dimensional inclusion pockets of (A) β-CD, (B) HP β-CD and (C) Captisol demonstrating (i) top view, (ii) bottom view (iii) side view (iv) top view with outlined interactions showing the bond lengths.

    Techniques Used:



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    Image Search Results


    Three-dimensional inclusion pockets of (A) β-CD, (B) HP β-CD and (C) Captisol demonstrating (i) top view, (ii) bottom view (iii) side view (iv) top view with outlined interactions showing the bond lengths.

    Journal: International Journal of Pharmaceutics: X

    Article Title: Formulation, in silico, in vitro characterization, cytotoxicity and cellular uptake of cyclodextrin complexes and ion pairing/salt formation with functional excipients (azelaic acid, tartaric acid, and arginine) with raloxifene

    doi: 10.1016/j.ijpx.2025.100336

    Figure Lengend Snippet: Three-dimensional inclusion pockets of (A) β-CD, (B) HP β-CD and (C) Captisol demonstrating (i) top view, (ii) bottom view (iii) side view (iv) top view with outlined interactions showing the bond lengths.

    Article Snippet: Beta (β)-cyclodextrin, and hydroxypropyl β-cyclodextrin (HP β-CD) were supplied by Acros Organics, New Jersey, USA. β-cyclodextrin sulfobutyl ether sodium salt (Captisol®) was a gift from CyDex Pharmaceuticals, Kansas, USA.

    Techniques:

    Equilibrium solubility of curcumin, curcumin: β-cyclodextrin, curcumin: Captisol, curcumin: hydroxypropyl β-cyclodextrin, and curcumin: hydroxyethyl β-cyclodextrin prepared by physical mixing (PM) and copreciptiation (Coppt), results presented as mean ± SD, n = 3.

    Journal: Pharmaceutics

    Article Title: Design, Preparation and Evaluation of Supramolecular Complexes with Curcumin for Enhanced Cytotoxicity in Breast Cancer Cell Lines

    doi: 10.3390/pharmaceutics14112283

    Figure Lengend Snippet: Equilibrium solubility of curcumin, curcumin: β-cyclodextrin, curcumin: Captisol, curcumin: hydroxypropyl β-cyclodextrin, and curcumin: hydroxyethyl β-cyclodextrin prepared by physical mixing (PM) and copreciptiation (Coppt), results presented as mean ± SD, n = 3.

    Article Snippet: Captisol (β-cyclodextrin sulfobutyl ether sodium salt) was a generous gift from CyDex Pharmaceuticals, Lawrence, KS, USA.

    Techniques: Solubility

    A–D . DSC thermograms of curcumin, curcumin: cyclodextrin complexes β-cyclodextrin ( A ), Captisol ( B ), hydroxypropyl β-cyclodextrin ( C ), and hydroxyethyl β-cyclodextrin ( D ) prepared by physical mixing (PM) and copreciptiation (Coppt).

    Journal: Pharmaceutics

    Article Title: Design, Preparation and Evaluation of Supramolecular Complexes with Curcumin for Enhanced Cytotoxicity in Breast Cancer Cell Lines

    doi: 10.3390/pharmaceutics14112283

    Figure Lengend Snippet: A–D . DSC thermograms of curcumin, curcumin: cyclodextrin complexes β-cyclodextrin ( A ), Captisol ( B ), hydroxypropyl β-cyclodextrin ( C ), and hydroxyethyl β-cyclodextrin ( D ) prepared by physical mixing (PM) and copreciptiation (Coppt).

    Article Snippet: Captisol (β-cyclodextrin sulfobutyl ether sodium salt) was a generous gift from CyDex Pharmaceuticals, Lawrence, KS, USA.

    Techniques:

    A–D. FTIR spectra of curcumin, curcumin: cyclodextrin complexes β-cyclodextrin ( A ), Captisol ( B ), hydroxypropyl β-cyclodextrin ( C ), and hydroxyethyl β-cyclodextrin ( D ) prepared by physical mixing (PM) and copreciptiation (Coppt).

    Journal: Pharmaceutics

    Article Title: Design, Preparation and Evaluation of Supramolecular Complexes with Curcumin for Enhanced Cytotoxicity in Breast Cancer Cell Lines

    doi: 10.3390/pharmaceutics14112283

    Figure Lengend Snippet: A–D. FTIR spectra of curcumin, curcumin: cyclodextrin complexes β-cyclodextrin ( A ), Captisol ( B ), hydroxypropyl β-cyclodextrin ( C ), and hydroxyethyl β-cyclodextrin ( D ) prepared by physical mixing (PM) and copreciptiation (Coppt).

    Article Snippet: Captisol (β-cyclodextrin sulfobutyl ether sodium salt) was a generous gift from CyDex Pharmaceuticals, Lawrence, KS, USA.

    Techniques:

    A–D. XRD spectra of curcumin, curcumin: cyclodextrin complexes β-cyclodextrin ( A ), Captisol ( B ), hydroxypropyl β-cyclodextrin ( C ), and hydroxyethyl β-cyclodextrin ( D ) prepared by physical mixing (PM) and copreciptiation (Coppt).

    Journal: Pharmaceutics

    Article Title: Design, Preparation and Evaluation of Supramolecular Complexes with Curcumin for Enhanced Cytotoxicity in Breast Cancer Cell Lines

    doi: 10.3390/pharmaceutics14112283

    Figure Lengend Snippet: A–D. XRD spectra of curcumin, curcumin: cyclodextrin complexes β-cyclodextrin ( A ), Captisol ( B ), hydroxypropyl β-cyclodextrin ( C ), and hydroxyethyl β-cyclodextrin ( D ) prepared by physical mixing (PM) and copreciptiation (Coppt).

    Article Snippet: Captisol (β-cyclodextrin sulfobutyl ether sodium salt) was a generous gift from CyDex Pharmaceuticals, Lawrence, KS, USA.

    Techniques: